TheStreet.com TV recently discovered this never-before-seen commercial for the just-cancelled Pfizer product. Could advertising like this have saved the product? thestreet.com

Demonstração do uso da exubera. A nuvem de insulina que menciono não dá para ver no vídeo porque ela é muito fraca no blister de 1mg.

FIRST FDA-APPROVED INHALED INSULIN, EXUBERA® (insulin human [rDNA origin]) Inhalation Powder, REDUCES BARRIERS FOR DIABETES PATIENTS TO ACHIEVE GOOD BLOOD SUGAR LEVEL CONTROL Diabetes is a growing health crisis, affecting nearly 21 million Americans. Most have type 2 diabetes -- a progressive disease -- and ultimately many will require insulin therapy. Despite the availability of insulin, a proven and effective treatment for diabetes, average blood sugar levels have continued to rise over the last 10 years. Approximately two out of three people with type 2 diabetes have uncontrolled blood sugar levels even if they are currently on treatment. Many patients are reluctant to start or increase insulin treatment because of injections. Some delay insulin use for as long as 10 years. For the first time, there is now an insulin that does not need to be injected. EXUBERA, the first and only FDA-approved inhaled insulin, is now available in pharmacies to help treat adults with type 1 or type 2 diabetes. Taking EXUBERA doesn't require needles.

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Since its discovery more than 80 years ago, insulin has been the gold standard treatment for diabetes In order to achieve tight blood sugar control, insulin is often administered before meals to mimic the body's natural insulin response to food Exubera is an innovative treatment for diabetes that reduces -- and sometimes eliminates - the need for injections

Insulina Inhalada

Pfizer inhaled insulin inovation

FDA recently approved Exubera, the first inhaled insulin product. It's a powdered form of recombinant human insulin that is self-administered using a specially designed inhaler. Exubera, manufactured by Pfizer, is intended to treat types 1 and 2 diabetes in patients over the age of 18. For patients with type 1 diabetes, Exubera can replace the short-acting insulin that is generally taken with meals, because with the inhaled form of insulin, patients can achieve peak levels of insulin quicker than with the injectable form. But Exubera doesn't replace their longer-acting insulin -- Type 1 diabetics will still have to take injections for that. With type 2 diabetics, Exubera can be used alone, or in combination with oral antidiabetic drugs or longer-acting injectable insulin. Because Exubera is a fine powder that could have an affect on the lungs, the drug isn't recommended in patients with underlying lung diseases such as poorly controlled asthma, COPD or emphysema. And it should not be used by smokers. It's also recommended that patients receive a baseline pulmonary function test prior to starting Exubera, with repeat tests after six months on the drug and then every year thereafter, even if there are no pulmonary symptoms. Pfizer will do long-term studies of the drug to continue to look at safety issues, such as the effect of Exubera on patients with underlying lung disease. Every time patients fill a prescription for Exubera, they'll be given a Medication Guide. The Guide explains how the drug is to be used, contraindications, and possible side effects. It also lets patients know about possible effects on the lungs, and about the need for periodic lung function tests.

Exubera

From Washington - Many war veterans and others who have been exposed to severely traumatic events can suffer from post-traumatic stress disorder. New research indicates that treatments routinely used for PTSD are not effective. However, the study did show that exposure therapy, wherein a traumatic event is relived again and again, was effective at causing the events to lose their potency. From New York - the pharma giant Pfizer is pulling its inhaled insulin product Exubera from the market. The product was initially believed to be a potential blockbuster, given the rising prevalence of diabetes and the fact that it can be used instead of injections. The drug is being pulled for business decisions as opposed to safety ones, as it never achieved significant market penetration. From Virginia - Following the death of a high school student from methicillin-resistant staph aureus, other cases are being diagnosed across the country. MRSA now causes more deaths in the US than HIV/AIDS. Health authorities are recommending high school students wash hands frequently, cover cuts and boils and avoid sharing personal items like towels, razors and tweezers. And finally, from Michigan - Using the Hepatitis A vaccine may be better than using immunoglobulins. A randomized clinical trial on over 1,000 patients showed there was no difference between the vaccine and the immunoglobulins, however the vaccine is cheaper and easier to obtain. For Insidermedicine in 60, I'm Dr. Susan Sharma.

Exubera, Sleeping Pills, Side Effects, Viagra, Breast Feeding

A little over a year ago I blogged about a company called Generex. Their flagship product is called Oral-lyn, a spray form of insulin that enters the body through the inner lining of the cheek. Imagine the future of coverage and correction without needles! Standby 'cause the future of needle-free insulin is closer than you think -- Phase 3 of clinical trials!

Type 1 diabetics need insulin-therapy to survive. So what exactly is insulin and why is it necessary?

La montaña, de intensos verdes, está cubierta por un exubera

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