UFR de Pharmacie 27, bd Jean Moulin -13385 Marseille Cedex 5 Directrice : Françoise Dignat-George

Here are the web sites: Advanced Nanotech research paper: http://www.iupac.org/publications/pac/2005/pdf/7710x1675.pdf Endothelium http://www.med.uio.no/rh/patologi/liipat/endothelium/ Reverse engineer the brain- it is a long video http://www.gmu.edu/thinklearn/decade/video7.html One not mentioned dealing with regulating nanotech http://www.rel-uita.org/nanotecnologia L'Oreal had, 500 patents in 2001 according to this http://www.smalltimes.com/articles/stm_print_screen.cfm?ARTI CLE_ID=268424 Elan Drug Technologies (Ireland)has a suite of more than 750 patents protecting its technology-based solutions and over 30 products launched in 40 countries worldwide. For fast commercial success of your poorly water-soluble compound or a Nanoformulation™ of your existing drug product, choose Elan's NanoCrystal® Technology.

BlazerCast for November 11, 2008: A nanomatrix for stent coating designed at the University of Alabama at Birmingham (UAB) mimics natural endothelium, the substance that lines blood vessels, and promises the potential to prevent post-operative tissue scaring along the blood vessel wall, greatly reducing the possibility of future thrombosis, or blockage at the stent site. This next generation nanotechnology could prove vital to reducing coronary artery disease, the number one cause of death in the United States, said Ho-Wook Jun, Ph.D., a UAB assistant professor of Biomedical Engineering and principal investigator on the discovery. Become a fan of BlazerCast on Facebook: http://www.facebook.com/pages/BlazerCast/20770581932 Follow us on Twitter: http://twitter.com/uabnews More Info Here: http://tinyurl.com/5zj8yx

Intac rings by Addition technology are used to add support to cornea's that have been weakened by thinning from kerataconnus or rarely ectasia from laser vision correction. The unique curved surface reduces glare. Many sizes are available. The Ziemer LDV FS laser here is equipted with an experimental head at 430um depth. A program allows for endless manipulation of the shape to be treated including tracks and the shape required for an inlay. Tissue bridge free track leads to smooth insertion without risk of the ring going off the track as can occur with Intralase. The track can be made narrow to create a tight fit. High numerical aperture means less energy in therory arrives on the endothelium unlike the micro joule lasers that can produce stress on the endothelium(AAO 07). Major advancement in lamellar surgery limited only by the imagination.

Big Bubble technique of deep anterior lamellar keratoplasty is an excellent technique of corneal surgery for a variety of corneal disorders wherein the endothelium is healthy such as in keratoconus. My set of instruments have been developed to simplify the learning curve of this technique of surgery, and make it possible to achieve the big bubble more consistently.

Deep Lamellar Keratoplasty for keratoconus. Preserves patient's own endothelium/Descemet to reduce rejection and better tectonic strength.

A surgical video demonstrating the technique for an anterior chamber intraocular lens exchange with a posterior chamber iris-sutured intraocular lens and simultaneous DSAEK

www.cellmedicine.com this is a description of the paper Galimi et al. Blood 205:2400 showing stem cells entering CNS in absence of injury

Characterization And Molecular Regulation Of Hemogenic Endothelium Within The Aorta-Gonad-Mesonephros (Agm) Region In The Midgestation Murine Embryo

for more info see www.stemcellpatents.com A review of a paper describing bone marrow stem cells ability to reverse dysfunction of aged endothelium.

intralase assisted DSEAK

Dr. Kiranjit Singh removes an angle supported AC IOL which was hurting the corneal endothelium and replaces it with an artisan lens. Also does a little anterior vitrectomy to make a better bed for the artisan lens.

Descemet dissection using an artificial chamber endothelium upside.

Genentech is alerting healthcare professionals about two new safety issues for Avastin or bevacizumab, a drug used to treat certain colorectal and lung cancers. The first is a rare brain-capillary leak problem called reversible posterior leukoencephalopathy syndrome (RPLS). RPLS is a neurological disorder associated with hypertension, fluid retention and the cytotoxic effects of immunosuppressive drugs on the vascular endothelium. The onset of symptoms can occur from 16 hours to 1 year after starting Avastin treatment. These symptoms can include headache, seizures, visual disturbances and altered mental function with or without hypertension. An MRI is needed to establish a diagnosis of RPLS. The company says that if your patient develops RPLS, you should stop Avastin therapy and start treating the hypertension, if present. Symptoms of RPLS usually resolve or improve within days, although some patients continue to have ongoing neurological sequela. It is not known whether it is safe to restart Avastin therapy in patients who have already experienced RPLS. The second safety issue concerns patients on Avastin who have experienced perforation of the nasal septum. Seven cases of this adverse event have been reported since the drug was marketed.

Preparation of DSEK donor tissue using moria artificial anterior chamber. The endothelium is stained using vision blue only for visibility for this videotaping.

Contributed by: (http://www.india-herbs.com): The goal of Ayurvedic medicine is to prevent diseases before they occur. Studies have suggested that Ayurveda may be particularly effective at reducing the risk of heart disease. For example, a recent study found that this traditional Indian medicine helped reduce plaque and reverse the thickening of artery walls known as atherosclerosis in both healthy adults as well as adults at high risk for heart disease. (Atherosclerosis is a slow, complex disease in which fatty substances, cholesterol, cellular waste products, calcium, and other substances build up in the inner lining of an artery. This build-up, also known as plaque, can lead to heart attack and stroke.) Combining yoga with an Ayurvedic herbal remedy containing Winter cherry (Withania somnifera), Boswellia (Boswellia serrata), and Turmeric (Curcuma longa) can reduce pain and disability if you have arthritis. What should I expect from an Ayurvedic treatment? Ayurvedic treatment focuses on rebalancing the doshas. On your first visit, the practitioner will take a detailed medical history, check your pulse, palpate your abdomen, examine your tongue, eyes, nails, and skin, and listen to the tone of your voice. He or she will also ask you questions about your general state of health with special focus on your lifestyle, diet, habits, and environmental surroundings. Based on this assessment, he or she will then make recommendations on how to restore your natural dosha balance, which almost always includes changes in lifestyle, particular diet. Practitioners draw from more than 20 types of treatment, but the most commonly prescribed include: • Pranayama -- breathing exercises. Practicing pranayama generates feelings of calmness. • Abhyanga -- rubbing the skin with herbalized oil (usually sesame oil is the base) to increase blood circulation and draw toxins out of the body through the skin. • Rasayana -- using mantras (repeated words or phrases) during meditation combined with specific herbs to rejuvenate a person. • Yoga -- combining pranayama, movement, and meditation. Has been shown to improve circulation and digestion, and to reduce blood pressure, cholesterol levels, anxiety, and chronic pain. • Pancha karma -- cleansing the body of toxins to purify the body and reduce cholesterol. Practitioners use methods to induce sweat, bowel movements, and even vomit in an effort to cleanse the body of toxins. • Herbal medicines -- prescribing herbs to restore dosha balance. Physiotherapy accompanied by herbal medication can alleviate the symptoms of a paralytic stroke. The vitalizing body massages prevent the inactive muscles from atrophying and medication helps to improve the circulatory system. Regular Panchakarma prevents stroke by maintaining normal blood pressure and keeping the arteries healthy. The endothelium of the arteries gets damaged due to accumulation of toxins and subsequent formation of thrombus. These thrombi, when dislodged, can cause stroke. Regular Panchakarma and Ayurveda lifestyle prevents this catastrophe. A number of Ayurvedic herbal remedes have been evaluated for their beneficial effects. For example, Guggulipid (Commiphora mukul), a traditional Ayurvedic medication used to treat high cholesterol, is widely used in India. It appears to effectively lower cholesterol by blocking the production of cholesterol in the liver. Similarly, fenugreek (Trigonella foenum graecum) seeds can decrease LDL cholesterol and triglycerides, and increase HDL cholesterol levels. These effects seem to be due to reduced intestinal absorption of cholesterol, and may be related to the high fiber content of the seed. Fenugreek seeds may also help control your blood sugars if you have diabetes, again because of the high fiber content. Other Ayurvedic herbs are being studied as treatments for Alzheimer's disease, anxiety, asthma, dementia, dysmenorrhea (painful menstruation), herpes, high blood pressure, Parkinson's disease, perimenopausal problems, and premenstrual syndrome, amongst many other conditions. Ayurvedic herbs combined with conventional medications may also be helpful for acne, chronic constipation, chronic fatigue syndrome, irritable bowel syndrome, obesity, and uterine fibroids. Be sure to consult your doctor before trying Ayurveda, especially if you take medicines or have certain dietary restrictions such as with diabetes.