'Referred pain' is a very unpleasant sensation localized to an area separate from the site of the causative injury or other
painful stimulation. Often, referred pain arises when a
nerve is compressed or damaged at or near its origin. In this circumstance, the sensation of pain will generally be felt in the territory that the nerve serves, even though the damage originates elsewhere.
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Examples
A common example is
spinal disc herniation, in which a nerve root arising from the
spinal cord is compressed by adjacent disc material. Although pain may arise from the damaged disc itself, pain and/or other symptoms will also be felt in the region served by the compressed nerve (for example, the
thigh,
knee, or
foot). Relieving the pressure on the nerve root may ameliorate the referred pain, provided that permanent nerve damage has not occurred.
A similar mechanism may be responsible for some instances of the
phantom limb syndrome in
amputees.
In another classic example of referred pain, male patients who are suffering a
myocardial infarction (heart attack) feel pain in their left arm. Another example of referred pain is the common "
ice cream headache" or "
brain freeze" which happens when the
trigeminal ganglion is indirectly stimulated from cold food on the roof of the mouth. Another example is pain from an inflamed
gall bladder which may refer pain to the right shoulder and pain from a
herniated cervical disc referring pain down one or both arms into the hands. In addition, tooth pain may refer pain that should be localized to the affected tooth to the opposite side of the mouth as opposed to actually feeling pain in the tooth with the
cavity or
abscess.
Mechanism
In cases of damage to
viscera, referred pain may be due to convergence of
visceral nerves that innervate the damaged organs with
somatic nerves that innervate sections of skin. Because a
neuron from the organ and one from the skin may form a
synapse with the same
projection neuron in the
dorsal horn, input from either neuron will be interpreted the same way by it and all neurons further up the pathway. Since the
brain is more "accustomed" to receiving sensation from the peripheral structure than from the viscera, it may interpret the pain as originating from the former. Thus there is an array of diseases that cause damage to organs and which produce characteristic patterns of pain in unrelated places in the body's periphery.
Despite the proliferation of literature on the mechanisms of referred pain, it is a process that is still not well understood.
Interestingly enough, there also seems to be some sort of pattern to referred pain in the symptoms associated with various disorders, for instance, many people are familiar with a physical symptom being associated with emotional distress, nausea, headaches, etc. but, there is a very minor chance that a person with a heart condition will have a tooth ache and no other obvious symptoms at all. Other examples include joint pain associated with a kidney infection or a digestive disorder being felt in a headache. It is not fully understood why these symptoms occur the way they do.
References
1. Referred pain from the spine
External links
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