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'Priscilla Barbara Elizabeth Bertie, 21st Baroness Willoughby de Eresby' (16 February 1761–29 December 1828) was a daughter of the 3rd Duke of Ancaster and Kesteven. On 23 February 1779, she married Sir Peter Burrell (later 1st Baron Gwydyr) and they later had two children. Through her grandmother Mary Wynn, Priscilla Bertie was a descendant of the Welsh princely house of Aberffraw.
On 8 July 1779, her brother, the 4th Duke of Ancaster and Kesteven died of scarlet fever at the age of 22 and his dukedom passed to his uncle, but his barony of Willoughby de Eresby, as well as the office of Lord Great Chamberlain, went into abeyance amongst Priscilla and her sister, the Countess of Cholmondeley. On 17 March 1780, however, the abeyance of the barony was terminated in Priscilla's favour as the eldest sibling. The office of Lord Great Chamberlain remains divided.