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'Prilocaine' (IPA: ) is a local anesthetic of the amino amide type. In its injectable form (trade name 'Citanest'), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA). As it has low cardiac toxicity, it is commoly used for intravenous regional anaesthesia (IVRA).
In some patients, a metabolite of prilocaine may cause the unusual side-effect of methaemoglobinaemia.