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'Plicatic acid' is a carboxylic acid from the resin acid group. It is naturally found in thuja and cypress resin. It is the main irritant and contact allergen present in thuja wood. (''Cf.'' pine, where the primary irritant is abietic acid.)
The highest concentration of plicatic acid can be found in ''Thuja plicata'' (Western Redcedar), but ''Thuja occidentalis'' (Eastern Arborvitae) and ''Cryptomeria japonica'' (Sugi) contain it in significant proportions as well.
Exposition to plicatic acid or thuja wood dust can worsen asthma and provoke allergic reactions.

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