(Redirected from Paromomycin)
'Paromomycin sulfate' (brand name 'Humatin'®) is a drug that fights intestinal infections such as
cryptosporidiosis and amoeba infection, or
amoebiasis and was developed as a therapeutic against
visceral leishmaniasis by the
Institute for OneWorld Health. Paromomycin was granted
orphan drug status in 2005
[1] and was approved by the Drug Controller General of India in September 2006 for treatment visceral leishmaniasis.
[1]
Paromomycin inhibits
protein synthesis by binding to 16S
ribosomal RNA.
[3]
References
1.
2.
3. Crystal Structure of Paromomycin Docked into the Eubacterial Ribosomal Decoding A Site, , Quentin, Vicens, Structure, 2001