'Mokola virus' is one of four members of the
lyssavirus genus found in
Africa, the others being
Duvenhage virus,
Lagos bat virus and classic
rabies virus. Mokola virus was first isolated from
shrews (''
Crocidura'' species) from Mokola forest,
Nigeria in 1968. It has caused two human deaths in Nigeria, in 1969
[1] and 1971
[2]. It causes lethal encephalitis, and does not manifest the features of classic
rabies.
Mokola virus has also been found in numerous other mammalian species in sub-Saharan Africa, including rodents, domestic cats in
Zimbabwe and
South Africa and a dog. Some of these cats had received
rabies vaccine but remained susceptible to Mokola virus infection.
The reservoir for Mokola virus is unknown. Unlike other lyssaviruses, Mokola virus is able to infect and replicate in
mosquito cells and so may be harboured by
insects.
References
1. Familusi, JB and Moore, DL. (1972). Isolation of a rabies related virus from the cerebrospinal fluid of a child with 'asceptic meningitis.' ''African Journal of Medical Science. '' '3':93–96.
2. Familusi, JB, Osunkoya, BO, Moore, DL, Kemp, GE, Fabiyi, A. (1972). A fatal human infection with Mokola virus. ''American Journal of Tropical Medicine and Hygiene. '' '21':959–963.