'Levetiracetam' (
INN) (
IPA: ) is an
anticonvulsant medication used to treat
epilepsy. It is ''S''-
enantiomer of
etiracetam, structurally similar to the prototypical
nootropic drug
piracetam. Along with other anticonvulsants like
gabapentin, it is also sometimes used to treat
neuropathic pain. Levetiracetam is marketed under the trade name 'Keppra'. Keppra is manufactured by UCB Pharmaceuticals Inc.
Levetiracetam has recently been approved in the United Kingdom as a monotherapy treatment for epilepsy. It is also used in veterinary medicine for similar purposes.
Side effects
Side effects include:
ataxia (sudden loss of balance);
hair loss;
pins and needles sensation in the extremities; psychiatric symptoms ranging from
irritability to
depression; and other common side effects like
headache and
nausea.
Recent literature
[1] (and paper 2.163 in
[2]) suggests that the addition of
pyridoxine (vitamin B6) may curtail some of the psychiatric symptoms.
References
★
Keppra (levetiracetam) Final Printed Label New and Generic Drug Approvals. 29 Dec 1999. Center for Drug Evaluation and Research, U.S. Food and Drug Administration. Accessed 31 August 2005.
★
SID 7847774 -- PubChem Substance Summary
External links
★
Keppra UCB (manufacturer's website)
★
NIH MedLine drug information
See also
★
Racetams