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{{Infobox Islands
| name = Isla Grande de Tierra del Fuego
| image name = Cities of Tierra del Fuego.png|250px
| image caption = Tierra de Fuego
| locator map =
| native name =
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| location = Tierra del Fuego
| coordinates =
| archipelago = Tierra del Fuego
| total islands =
| major islands =
| area = 47,992 km² (29,820 ft²}
| highest mount = Mount Darwin
| elevation = 2,488 metres / 8,163 ft
| country =
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| country 1 = Argentina
| country 1 admin divisions title = Tierra del Fuego Province
| country 1 admin divisions = Tierra del Fuego Province (Argentina}
| country 1 largest city = Ushuaia
| country 1 largest city population = 64,000
| country 2 = Chile
| country 2 admin divisions title = Magallanes y Antártica Chilena Region
| country 2 admin divisions = Tierra del Fuego Province, Chile
| country 2 largest city = Porvenir
| country 2 largest city population = 4,807
| population =
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}}
'Isla Grande de Tierra del Fuego' (literally, ''Great Island of the Land of Fire'') is an island near the southern tip of South America from which it is separated by the Strait of Magellan. Its western part is in Chile (Province of Tierra del Fuego and Antártica Chilena Province), while the east is in Argentina (Tierra del Fuego Province). It forms the major landmass in the island group also called Tierra del Fuego.
The island has an area of 47,992 km², making it the 29th largest island in the world. Its two primary towns are Ushuaia and Río Grande, both in Argentina, while its highest point is Monte Darwin (2,488 m), in Chile. Other towns are Tolhuin and Porvenir in Argentina and Chile respectively. The northern parts of the island have oil deposits, Cerro Sombrero in Chile is the main extraction centre in the island.