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'Hemisphere' may refer to:

★ Half of a sphere
As half of 'the Earth':

★ Any half of the Earth or other planetary or stellar body

★ New World

★ Old World

★ Western Hemisphere

★ Eastern Hemisphere

★ Northern Hemisphere

★ Southern Hemisphere

★ Land hemisphere

★ Water hemisphere
As half of the 'brain':

★ Cerebral hemisphere, a division of the cerebrum

★ Half of the cerebellum, a smaller part of the brain
In 'music':

★ ''Hemispheres'' (Rush album), by Rush

★ ''Hemispheres'' (Anthony Davis album), by Anthony Davis

★ ''Hemispheres'' (Dan Siegel album), by Dan Siegel

★ ''Hemispheres'' (Doseone album), by Doseone
'Other':

★ Any half of the celestial sphere

★ ''Hemispheres'' (magazine), an inflight publication

★ ''Hemispheres'' (TV series), Canadian and Australian news program

★ L'Hemisfèric at the Ciutat de les Arts i les Ciències, Valencia, Spain.