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'HSI', a Three-Letter Acronym meaning:

★ 'H'ang 'S'eng 'I'ndex

★ Horizontal Situation Indicator, an aircraft instrument combining navigation and heading information on one simplified display. Combining a CDI with a DG. It's a poor mans Flight director (aviation).

★ 'H'uman 'S'ystems 'I'ntegration - a discipline within systems engineering that incorporates human-related factors into total system life-cycle design considerations

★ 'H'igh 'S'peed 'I'nput for microcontrollers

★ 'H'igh 'S'peed 'I'nternet

★ Hue, Saturation, Intensity Color Space

★ High Speed Interconnect: a bridge chip designed by NVIDIA to make PCI Express chips available for the AGP slot, and vice-versa

★ Health Sciences Institute: A website that advertises alternative medicine.

★ Hispanic-Serving Institution

★ 'H'ot 'S'urface 'I'gnitor for gas furnaces and hot water heaters.

★ Habitat suitability index for formulating environmental models for species distribution

★ Heat Stress Index: A relative index that evaluates how people respond to variable meteorological conditions.

★ 'H'epato 'S'omatic 'I'ndex