Main articles: Eosin
'Eosinophilic' means "loves eosin", and refers to the
staining of certain
tissues,
cells, or
organelles after they been washed with
eosin, a
dye.
Eosin is an
acidic dye, thus the structure being stained is
basic.
Eosinophilic describes the appearance of cells and structures seen in
histological sections which take up the staining dye,
eosin. This is a bright pink dye that stains the cytoplasm of cells as well as extracellular proteins such as
collagen.
Such eosinophilic structures are generally composed of
protein.
The stain eosin is usually combined with a stain called
haematoxylin to produce a haematoxylin and eosin stained
section (also called an H&E, HE or H+E section). This is the most widely used histological stain in medical diagnosis - for example when a
pathologist looks at a
biopsy of a suspected cancer they will have the section stained with H&E.
Some structures seen inside cells are described as being eosinophilic, for example
Lewy bodies,
Mallory bodies.
See also
★
basophilic (affinity to
hematoxylln)
★
Eosinophilia