In
anatomy of the
digestive system, the 'duodenum' is a hollow jointed tube connecting the
stomach to the
jejunum. It is the first and shortest part of the
small intestine and it is where most chemical digestion takes place. It begins with the
duodenal bulb and ends at the
ligament of Treitz. The name ''duodenum'' is from the
Latin ''duodenum digitorum'', twelve fingers' breadths or inches.
Function
The duodenum is largely responsible for the breakdown of food in the small intestine.
Brunner's glands, which secrete
mucus, are found in the duodenum. The duodenum wall is composed of a very thin layer of cells that form the
muscularis mucosae. The duodenum is almost entirely
retroperitoneal. The
pH in the duodenum is approximately six.
Sections
The duodenum is divided into four sections for the purposes of description. The first three sections form a "C" shape.
First part
The first (superior) part began as a continuation of the duodenal end of the
pylorus. From here it passes laterally (right), superiorly and posteriorly, for approximately 5 cm, before making a sharp curve inferiorly into the superior duodenal flexure (the end of the superior part). It is intraperitoneal.
Second part
The second (descending) part of the duodenum begins at the superior duodenal flexure. It passes inferiorly to the lower border of vertebral body L3, before making a sharp turn medially into the inferior duodenal flexure (the end of the descending part).
The
pancreatic duct and
common bile duct enter the descending duodenum, commonly known together as the
hepatopancreatic duct (or
pancreatic duct in the United States), through the major duodenal
papilla. This part of the duodenum also contains the minor duodenal papilla, the entrance for the
accessory pancreatic duct. The junction between the embryological
foregut and
midgut lies just below the major duodenal papilla.
Third part
The third (inferior/horizontal) part of the duodenum begins at the inferior duodenal flexure and passes transversely to the left, crossing the
inferior vena cava,
aorta and the
vertebral column.
Fourth part
The fourth (ascending) part passes superiorly, either anterior to, or to the right of, the aorta, until it reaches the inferior border of the body of the
pancreas. Then, it curves anteriorly and terminates at the
duodenojejunal flexure where it joins the
jejunum. The duodenojejunal flexure is surrounded by a peritoneal fold containing muscle fibres: the
ligament of Treitz.
Additional images
References
1.
External links
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