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'Depression' may refer to:

★ Depression (mood), a common term for a sad or low mood or the loss of pleasure; an emotion that does not affect capacity to perform personal and vocational obligations

★ Clinical depression, or major depressive disorder, a state of intense sadness, melancholia or despair that has advanced to the point of being disruptive to an individual's social functioning and/or activities of daily living

★ Depression (geology), a sunken geological formation

★ Depression (economics), a longer-lasting and more severe economic downturn than a recession

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★ The Great Depression, a severe economic recession in the 1930s

★ Depression (meteorology), an area of low atmospheric pressure associated with cyclones and weather fronts

★ Depression (physiology), a lowering, in particular a reduction in a particular biological variable or the function of an organ, contrasted to ''elevation''

★ Depression (kinesiology), an anatomical term of motion