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DANAPAROID


'Danaparoid sodium' (Orgaran®) is an anticoagulant that works by inhibiting activated factor X (factor Xa).
Danaparoid is considered a "low molecular weight heparin" by some sources, but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients.

Contents
Uses
Discontinuation
Administration
Side effects
References
External links

Uses


It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery.
It is also used as a heparinoid substitute in heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis.

Discontinuation


On August 14, 2002, this drug was withdrawn by Organon International.[1]

Administration


IV

Side effects



★ Bleeding problems

Low platelets, due to a low level of structural similarity between danaparoid and heparin

Asthma exacerbations, due to allergies to sulphites contained within the medicine

References


1. Danaparoid (Subcutaneous Route) - MayoClinic.com

External links





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