'Danaparoid sodium' (Orgaran®) is an
anticoagulant that works by inhibiting activated
factor X (factor Xa).
Danaparoid is considered a "
low molecular weight heparin" by some sources, but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients.
Uses
It is used to prevent
deep venous clots, particularly in situations with a high risk of clot formation, such as after
hip surgery.
It is also used as a heparinoid substitute in
heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis.
Discontinuation
On August 14, 2002, this drug was withdrawn by
Organon International.
[1]
Administration
IV
Side effects
★ Bleeding problems
★
Low platelets, due to a low level of structural similarity between danaparoid and
heparin
★
Asthma exacerbations, due to allergies to
sulphites contained within the medicine
References
1. Danaparoid (Subcutaneous Route) - MayoClinic.com
External links
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