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'''Taxus canadensis''' ('Canadian Yew') is a conifer native to central and eastern North America, thriving in swampy woods, ravines, riverbanks and on lake shores. Locally called simply "Yew", this species is also referred to as American Yew or Ground-hemlock.
It is a sprawling shrub, rarely exceeding 2.5 m tall. It has thin scaly brown bark. The leaves are lanceolate, flat, dark green, 1-2.5 cm long and 1.5 mm broad, arranged in two flat rows either side of the.
The seed cones are highly modified, each cone containing a single seed partly surrounded by a modified scale which develops into a soft, bright red berry-like structure called an aril, open at the end. The seed are eaten by thrushes, waxwings and other birds, which disperse the hard seeds undamaged in their droppings. The male cones are globose, 3 mm diameter. It is a monoecious plant – one of the few in the genus.

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Uses and traditions

References

Uses and traditions

While one would be ill-advised to consume this plant, it is none-the-less thought to be of lower toxicity than ''Taxus baccata''. All parts of the plant, save the aril, should be considered toxic.
Tribes in its native range used small quantities of yew leaf tea topically or internally for a variety of ailments – notably rheumatism. Tribes are also been said to have used yew twigs in steam baths to help alleviate rheumatism. Again, it should be noted that the plant is still quite toxic and modern herbalists prefer safer, more effective herbs.
''Taxus canadensis'' is also being harvested in northern Ontario, Québec and Atlantic Canada as the plant is a source of the class of poisonous chemicals known as taxanes, which have been a focus for cancer research. ''T. canadensis'' is much more abundant than the near-threatened ''Taxus brevifolia'' (Pacific Yew), and the "greens" (new growth) can be harvested sustainably every five years, instead of stripping the bark and killing the plant.
The most abundant taxane in ''T. canadensis'' is 9-dihydro-13-acetylbaccatin III, which can be effectively converted to 10-deacetylbaccatin III, used in the production of paclitaxel. Recently, two new taxanes have been identified from ''T. canadensis'', including 7β,10β,13α-triacetoxy-5α-(3'-dimethylamino-3'-phenylpropanoyl)oxy-2α-hydroxy-2(3→20)abeotaxa-4(20),11-dien-9-one and 2α,10β-diacetoxy-9α-hydroxy-5α-(3'-dimethylamino-3'-phenylpropanoyl)oxy-3,11-cyclotax-4(20)-en-13-one.

References

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★ Gunawardana, G. P. ''et al.'' (1992). Isolation of 9-dihydro-13-acetylbaccatin III from Taxus canadensis. ''J. Nat. Prod.'' 55 (11): 1686-1689.

★ Nikolakakis, A. ''et al.'' (2000). Taxus canadensis abundant taxane : Conversion to paclitaxel and rearrangements. ''Bioorg. Med. Chem.'' 8 (6): 1269-1280.

★ Shi, Q. W. ''et al.'' (2006). Two new alkaloidal taxoids from the needles of ''Taxus canadensis''. ''Biosci. Biotechnol. Biochem.'' 70 (3): 732-6