'Anabolism' is the set of
metabolic pathways that construct molecules from smaller units, these reactions require
energy. One way of categorizing
metabolic processes, whether at the
cellular, organ or organism level is as 'anabolic' or '
catabolic', which is the opposite. Anabolism is powered by catabolism, where large molecules are broken down into smaller parts and then used up in
respiration. Many anabolic processes are powered by
adenosine triphosphate (ATP).
Anabolic processes tend toward "building up"
organs and
tissues. These processes produce growth and differentiation of cells and increase in body size, a process that involves
synthesis of complex
molecules. Examples of anabolic processes include growth and mineralization of
bone and increase of
muscle mass.
Endocrinologists have traditionally classified
hormones as anabolic or catabolic, depending on which part of metabolism they stimulate. The classic anabolic hormones are the
anabolic steroids, which stimulate protein synthesis and muscle growth.
Classic anabolic hormones
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Growth hormone
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IGF1 and other
insulin-like growth factors
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Insulin
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Testosterone
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Oestrogen
Newer hormones associated with the balance of the catabolic and anabolic states include
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Osexin and
Hypocretin (a hormone pair)
★
Melatonin
See also
★
Metabolism
★
Anabolic steroid