(Redirected from Alpha granules)In
platelets, the term "alpha granules" is used to describe
granules containing several growth factors (such as
insulin-like growth factor 1,
platelet-derived growth factor,
TGFβ),
platelet factor 4 which is a heparin-binding chemokine, and other
clotting proteins (such as
thrombospondin and
fibronectin.) The alpha granules express the adhesion molecule
P-selectin. The other type of granules within platelets are called
dense granules.
A deficiency of alpha granules is known as
grey platelet syndrome.
See also
★
Dense granule
External links
★
Platelet alpha-granules., Harrison P, Cramer E, , , Blood Rev, 1993