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ALAMETHICIN

'Alamethicin' is a peptide antibiotic, produced by the fungus ''Trichoderma viride''. It contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. The peptide sequence is:
Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phl
(Ac = acetyl, Phl = phenylalaninol)

★ Molecular Formula: C92H150N22O25

CAS number: 27061-78-5

★ Appearance: Off white solid

★ UV spectrum maxima: 265, 257

★ Melting point: 255°C-270°C

★ Solubility information: DMSO, Methanol, Ethanol. Not soluble in water
In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules.
data copied from Fermentek Alamethicin product page

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