(Redirected from Aitiology)
'Etiology' (alternately 'aetiology', 'aitiology') is the study of
causation. Derived from the
Greek αίτιολογία, "giving a reason for" (αἰτία "cause" +
-λογία).
[1]
The word is most commonly used in medical and philosophical theories, where it is used to refer to the study of why things occur, or even the reasons behind the way that things act, and is used in
philosophy,
physics,
psychology, government, and
medicine, and
biology in reference to the causes of various phenomena. An 'etiological myth' is a
myth intended to explain a name or create a mythic history for a place or family.
Medicine
In medicine in particular, the term refers to the causes of
diseases or
pathologies.
[2] Etiological discovery in medicine has a history in
Robert Koch's demonstration that the tubercle bacillus (''
Mycobacterium tuberculosis'' complex) causes the disease
tuberculosis, that ''
Bacillus anthracis'' causes
anthrax, and that
cholera is caused by ''
Vibrio cholerae''. This line of thinking and evidence is summarised in
Koch's postulates. Proof of causation in infectious diseases is limited, however, to individual cases that provide experimental evidence of etiology.
In epidemiology, several lines of evidence taken in aggregate are required to infer causation.
Sir Adrian Bradford-Hill demonstrated a causal relationship between smoking and lung cancer, and summarised the line of reasoning in the
epidemiological criteria for causation. Dr.
Al Evans, a US epidemiologist, put forward the
Unified Concept of Causation, a synthesis of the predecessors' ideas.
Etiological research in medicine has required further thinking in epidemiology - we may distinguish what is seen to be associated or statistically correlated, as due to several possible relationships. Things may be associated in observation due to chance, or due to bias or confounding, as well as due to causation (or reverse causation). Careful sampling and measurement are more important in teasing out causation from chance, bias or confounding than sophisticated statistical analyses. Experimental evidence, involving interventions (providing or removing the supposed cause) gives the most compelling evidence of etiology.
Thus etiology may be one part of a chain of causation. An etiological agent (''sine qua non'') of disease may require an independent co-factor (necessary but not sufficient), and be subject to a promoter (increases expression) in producing a disease. An example of all the above would be the late recognition that
peptic ulcer disease may be induced by stress, requires the presence of acid secretion in the stomach, and have primary etiology in ''
Helicobacter pylori'' infection. Many chronic diseases of unknown cause may be studied in this frame of reference to explain multiple epidemiological associations or risk factors which may or may not be causally related, and to seek the actual etiology.
Some diseases, such as
diabetes, are defined by their
symptoms and therefore can have more than one etiology.
Mythology
An 'etiological myth' is a
myth intended to explain the origins of cult practices, natural phenomena, proper names and the like. For example, the name
Delphi and its associated deity, ''
Apollon Delphinios'', are explained in the
Homeric Hymn which tells how Apollo carried
Cretans over the sea in the shape of a
dolphin ("delphis") to make them his priests. While Delphi is actually related to the word ''delphys'' ("womb"), many etiological myths are similarly based on
folk etymology (the term "
Amazon", for example). In the ''
Aeneid'' (published circa 17 BC),
Vergil claims the descent of
Augustus Caesar's Julian clan from the hero
Aeneas through his son Ascanius, also called Julus. Other examples of etiological myth come from the Bible, such as the setting of the rainbow in the heavens as a sign of God's
covenant with
Noah (Genesis 9); or the story of
Lot's wife in Genesis 19 (specifically 26), which explains why there are pillars of salt in the area of the
Dead Sea.
[3] The story of
Prometheus' sacrifice-trick in
Hesiod's ''
Theogony'' relates how Prometheus tricked
Zeus into choosing the bones and fat of the first sacrificial animal rather than the meat to justify why, after a sacrifice, the Greeks offered the bones wrapped in fat to the gods while keeping the meat for themselves.
See also
★
Eschatology
★
Geomythology
★
Just-so story (comparable to etiological myth)
References
1. Aetiology, , , , Oxford University Press, 2002,
2. The three C's of etiology Greene J Discusses several examples of the medical usage of the term ''etiology'' in the context of cleft lips and explains methods used to study causation.
3. Oxford Annotated Edition, Revised Standard Version of the Bible, , , , , 1973,
External links